deca durabolin reviews

Refers to the list II of the list of narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation. The main pharmacological properties omnopona caused therein morphine . deca Durabolin reviews agonist predominantly mu-opioid receptor, it activates endogenous antinociceptive system and thus gives interneuronal transmission of pain impulses at different levels of the central nervous system and alter emotional pain by acting on the higher parts of the brain.

Omnopon increases the pain threshold, inhibits the conditioned reflexes, causes euphoria and has a mild sedative and a central antitussive effect, increases the tone of the center of the vagus nerve, excites the center of vomiting, depresses the respiratory center, causing constriction of the pupil due to the activation center of the oculomotor nerve, weakens the intestinal peristalsis, inhibits secretory activity of the glands of the gastrointestinal tract. Several reduced basal metabolic rate and body temperature. It stimulates the release of antidiuretic hormone. When administered subcutaneously omnopona analgesic effect develops in 10-15 minutes and lasts for 3-5 hours. Papaverine hydrochloride – antispasmodic, hypotensive effect, lowers the tone and relaxes the smooth muscles of internal organs and blood vessels. Due to the content of papaverine omnopon less than morphine causes smooth muscle spasm of the internal organs. Codeine is a naturally occurring group of narcotic analgesic opioid receptor agonists. Analgesic deca durabolin reviews  activity is due to the excitation of opioid receptors in different parts of the central nervous system and peripheral tissues, leading to stimulation of the antinociceptive system and change the emotional perception of pain. Narcotine – opioid alkaloid that suppresses the cough center.

Indications
Severe pain of various origins of both acute and chronic nature of the hook (myocardial infarction, trauma, post-traumatic period, malignant neoplasms, in preparation for surgery and in the postoperative period, etc.). Pain syndrome (renal, hepatic, intestinal colic combination with antispasmodics myotropic action atropine or means).

Contraindications
: Hypersensitivity to the drug.
State, accompanied by respiratory depression or severe depression of the central nervous system. Spasmodic state. Increased intracranial pressure. Head injury.
Bronchial asthma. Paralytic ileus. Heart failure due to chronic lung disease. Cardiac arrhythmias.
Acute surgical diseases of the abdominal cavity before the diagnosis. Status after surgery on the biliary tract. Joint reception with inhibitors of monoamine oxidase, and within 14 days after their cancellation.
Children under 2 years old.
During pregnancy, childbirth and breast-feeding during the use of omnopona permissible only for health reasons (possible development of drug dependence deca durabolin reviews  in the fetus and newborn). Precautions – elderly patients, with general exhaustion, liver and kidney failure, adrenal cortex, patients with a history is an indication to the dependence to opioids.

Dosing and Administration
Doses are selected individually depending on the severity of pain, age and condition of the patient.
Usually, adults are injected subcutaneously with 1 ml of 1% or 2% solution. If necessary, re-preparation is administered within 4 hours of -5. The highest single dose – 30 mg (3 mL of a 1% solution or 1.5 mL of 2% solution), the highest daily dose – 100 mg (10 ml of a 1% solution or 5 mL of 2% solution).
Children older than 2 years, the drug is administered in a dosage of 1 mg (age 2-3 years) 7.5 mg (age 12-14 years) with allowance for general condition and the required degree of analgesia.

Side effects:
euphoria, urination disorders, allergic reactions, depression, hallucinations, nausea, sometimes vomiting, dizziness, muscle weakness, and constipation. It is also possible drowsiness or agitation, exacerbation of diseases of the brain due to increased intracranial pressure, spasms of the biliary tract and the bladder sphincter, moderate respiratory depression. To reduce the side effects on the intestine should be prescribed laxatives
dampening effect on the central nervous system anesthetic drugs, hypnotics, sedatives, antihistamines with a central component of action of antidepressants, anxiolytics and antipsychotics. It is addictive and drug (opioid) dependence (physical and mental). It causes dilation of peripheral blood vessels and the release of histamine, which may lead to bronchoconstriction, hypotension. redness of the skin, increased sweating, redness of the protein membranes of the eyes.
Repeated application omnopona within 1-2 weeks (sometimes 2-3 days) may develop addiction (weakening of the analgesic effect) and opioid drug dependence. After 1-2 days after discontinuation of the drug may be signs of withdrawal (mydriasis, yawning, muscle contraction, headache, sweating, vomiting, deca durabolin reviews  diarrhea, tachycardia, hyperthermia, hypertension and other autonomic symptoms) that require treatment in a specialized department.

Overdose Symptoms : stuporous or comatose, hypothermia, reduction in blood pressure is observed respiratory depression. A characteristic feature is a pronounced constriction of the pupils (pupils with significant hypoxia may be extended). Treatment : maintenance of adequate pulmonary ventilation. Intravenous administration of a specific opioid antagonist naloxone at a dose of 0.4 to 2 mg respiration recovers quickly. If no effect within 2-3 minutes of administration of naloxone is repeated. The initial dose of naloxone for children – 0.01 mg / kg. Keep in mind the short duration of action of naloxone. It should also be aware of the possibility of withdrawal symptoms upon administration of naloxone to patients with addiction to morphine and the like but means – in such cases, the antagonist dose should be increased gradually.

Interaction with other drugs
under close supervision and in small doses should be used omnopon on the background of anesthetic drugs, hypnotics, anxiolytics. antidepressants and neuroleptics in order to avoid excessive depression of the central nervous system and the suppression of the respiratory center activity. Omnopon should not be combined with narcotic analgesics from the group of partial agonists (buprenorphine, tramadol) and agonist-antagonists (nalbuphine, butorphanol) opioid receptor iz-za danger of weakening analgesia and possible provoke withdrawal symptoms.
The analgesic effect and adverse effects of opioid agonists (promedola, fentanyl ) in a therapeutic dose range are added to omnopon effects.

Cautions
In the period of treatment should refrain from activities potentially hazardous deca durabolin reviews  activities that require high concentration and psychomotor speed reactions.